Biomedical Simulation Visualization

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Image shows how a cancer cell flows over the white blood cell without any bond interactions or deformation. Solid walls (including the cells) are colored by flow velocity and the lines are velocity contours. 
 
Image courtesy of Meghan Hoskins, a Ph.D. candidate in the Bioengineering program at Penn State. Click this link for the full story on how "Cutting-edge CFD Simulations Take Cancer Research to a New Dimension".

 

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Simulation of an aneurysm of a cerebral artery. The streamlines represent the blood velocity. Warm colors represent regions of high velocity, and cool colors represent regions of low velocity. Click on this link to read the full story, Computer Visualization Paves the Way for Future Detection and Treatment of Aneurysms.


Visualization by Karla Vega, Texas Advanced Computing Center , The University of Texas at Austin

Data courtesy of Yuri Bazilevs, Victor Calo and Thomas J. R. Hughes, The Institute for Computational Engineering and Sciences, The University of Texas at Austin.

 

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Flow Sensitive 4D Magnetic Resonance Imaging (MRI)
 
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Example for anatomical and blood flow visualization in a patient with enlarged aorta (ascending aortic aneurysm, arrows). A: Maximum Intensity projection (MIP) of a coronal MR- Angiogram (MRA) B: Thin slab MIP, reformatted to a sagittal plane. C: Reconstructed thoracic aortic geometry using intensity based surface rendering. D: Late systolic streamlines reflecting the considerable helical flow in the region of the enlarged aorta.
 

Recent advances in medical imaging technology have allowed the acquisition of high-resolution, transient, three-dimensional images of blood flows within the human circulatory system. It is only natural that EnSight, widely used for visualizing blood flows computed in CFD simulations, be applied to the visualization of such complex medical imaging data providing compressive anatomical (blood vessel) and functional (blood flow) coverage of an entire organ of interest. 

CEI's medical imaging page, click here, includes a brief summary of the method, recent results and several references to articles in medical literature on this unique application of EnSight in the medical field. CEI has established a partnership with the Department of Diagnostic Radiology, Medical Physics at the University Hospital of Freiburg, a leading user of EnSight for flow sensitive 4D MR imaging, to aid others interested in using the software. 

 

For details, contact:
 
PD Dr. Michael Markl
Department of Diagnostic Radiology, Medical Physics
University Hospital Freiburg, Germany
This e-mail address is being protected from spambots. You need JavaScript enabled to view it

 

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Animation shows stent/balloon inflation dynamics and the impact that this has on peak arterial stresses.  During inflation, the stent has a tendency to flare at the ends due to the balloon overhang.  Increased overhang results in increased stent endflare and peak arterial stresses.  This, in turn, can increase the chances of restenosis (uncontrolled cell growth leading to the artery clogging back up).  The model is currently being adjusted to test high-pressure and high-resistance lesions. Courtesy of Matt Hyre, Jim Squire and Raevon Pulliam from the Virginia Military Institute.

 

Do you have an image or animation to be featured in an upcoming issue of CEI News? Submit it to the This e-mail address is being protected from spambots. You need JavaScript enabled to view it .

 
EnSight animation showing the blood-flow patterns during the systolic cycle. The computer model is a close approximation of the computer tomography model of a middle cerebral artery segment of a 57 year-old male with cerebral aneurysm. 
 
To read the full article on this story, click here.
 

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